Insulin-producing cells grown from patient’s blood safe for transplant

Researchers achieve milestone in efforts to get patients with diabetes off injected insulin for good

Insulin-producing cells grown from patient’s blood safe for transplantDiabetes researchers are reporting early success in a first-in-humans clinical trial to test whether pancreatic cells grown from a patient’s own blood can be safely implanted and begin to produce insulin. The team reported on their proof of concept and safety study in a newly published paper in the journal Cell Reports Medicine. Of 17 patients who…

‘Male menopause’ is real and treatable, say pharmacy researchers

New guidelines helps identify and treat testosterone deficiency as men age

‘Male menopause’ is real and treatable, say pharmacy researchersFatigue, weight gain and low libido are just three of the symptoms middle-aged and older men face as their testosterone levels decline, but many don’t realize what’s going on. Sometimes referred to as “male menopause” or “manopause” in reference to the symptoms women experience when their estrogen levels drop, the medical term for men is…

Agreement signed to train more Indigenous physicians

Six northeastern Alberta First Nations partner with the U of A to improve health care for their members

Agreement signed to train more Indigenous physiciansSix northeastern Alberta First Nations have formed a new partnership with the University of Alberta to train more Indigenous physicians and improve health care for their members. The memorandum of relational understanding between the university and Tribal Chiefs Ventures Inc., which represents Beaver Lake Cree Nation, Cold Lake First Nation, Frog Lake First Nation, Heart Lake…

Alberta expanding wastewater testing for SARS-CoV-2

Real-time infection rates to be tracked on public website

Alberta expanding wastewater testing for SARS-CoV-2Alberta can now track the prevalence of COVID-19 infections in nearly 75 per cent of the population thanks to the new Pan-Alberta Network for Wastewater-based SARS-CoV-2 Monitoring announced on Wednesday. When someone is infected with COVID-19 – whether they know it or not – traces of the virus are shed through the bowel and end up…

What parents need to know about the COVID-19 vaccine for kids

Two infectious disease experts answer your questions

What parents need to know about the COVID-19 vaccine for kidsEver since Canada approved the child-sized Pfizer-BioNTech vaccine against COVID-19 and started to distribute nearly three million doses, some parents have jumped at the chance to get their kids vaccinated, while others still have questions. “Even before it was approved, about 50 per cent of parents were already very eager to immunize their children as soon as possible,” said…

Does prescribed opioid use in children lead to later drug misuse?

Calls for rigorous research to determine if short-term medical use in children is safe

Does prescribed opioid use in children lead to later drug misuse?Pediatric researchers are calling for more rigorous research into the possible link between short-term opioid use for pain management in childhood and opioid use disorder later in life. The University of Alberta team reviewed the results of 21 previous studies but found no definitive answer to the question, according to a new study published this week in…

Made-in-Alberta vaccine and drug development pipeline gets funding

Alberta invests $55.1M to taking vaccines, antiviral drugs from discovery to manufacturing

Made-in-Alberta vaccine and drug development pipeline gets fundingAlberta is building a better pipeline, but this one’s not for oil and gas products – it’s for vaccines and therapeutic drugs to fight viral diseases. The province announced a $55.1-million grant on Wednesday for University of Alberta research on ways to prevent and treat COVID-19, including $15 million for vaccine projects and $10 million for studies…

Flawed breast screening studies may have led to death of thousands

An influential breast cancer screening trial was not randomized properly and should be withdrawn, new evidence shows

Flawed breast screening studies may have led to death of thousandsThousands of Canadian women may have died needlessly of breast cancer because of the fallout from two flawed studies on breast screening, according to a group of prominent researchers. In a commentary published in the Journal of Medical Screening, the researchers say they have new evidence that the Canadian National Breast Screening trials carried out in the 1980s were…

Just stop talking about weight with kids, says public health PhD grad

Research explores the impact of obesity-related stigma on young people – and how to end it

Just stop talking about weight with kids, says public health PhD grad“We should just keep weight out of everyday conversation with our kids.” That’s the conclusion Alexa Ferdinands came to after interviewing young people about their experiences with obesity-related stigma for her PhD in health promotion and socio-behavioural sciences in the University of Alberta’s School of Public Health. “When it comes to nutrition, there are so…

Nursing grad provides safe support for people affected by violence

The right person to talk to at the right time for people affected by violence

Nursing grad provides safe support for people affected by violenceRoohi Dodd knows that having the right person to talk to at the right time can make all the difference, which is why she is devoting her career to providing support for those affected by violence. Set to graduate with her BScN from the University of Alberta’s Faculty of Nursing, Dodd is already working as…

Obesity, Type 2 diabetes leading risk factors for severe COVID-19

Link could hold the key to improving immune responses against COVID-19 and other viruses

Obesity, Type 2 diabetes leading risk factors for severe COVID-19A little-understood link between insulin resistance in cells and obesity could hold the key to improving immune responses against COVID-19 and other viruses, according to University of Alberta researcher Sue Tsai. “We hypothesize that insulin resistance in immune cells such as B cells is a major link between obesity and an impaired antiviral response, leading…

SARS-CoV-2 uses sugars to invade human cells, new study shows

Understanding the process could help scientists look out for new, more infectious variants

SARS-CoV-2 uses sugars to invade human cells, new study showsSugars found on the surface of human cells influence COVID-19 infection, according to a University of Alberta-led study that’s one of the first to observe this relationship and suggests that cells in the brain might be particularly susceptible. “The idea here is that the virus is leveraging or using the host glycans, or the host sugars,…

Muslim Seniors Research works to improve health, fight Islamophobia

Unique research links academic findings with concrete change for Muslim communities

Muslim Seniors Research works to improve health, fight IslamophobiaFor Jordana Salma, academic research should be a two-way street: an ongoing cycle of asking questions, identifying concerns and then working with communities to address them. The assistant professor in the University of Alberta’s Faculty of Nursing relies on Alberta’s Muslim community to guide her studies of aging and health for seniors. In return, she promises to…

Discovery shows promise for safer, more effective COVID-19 treatments

Protease inhibitor compounds interfere with the SARS-CoV-2 virus’s ability to replicate itself

Discovery shows promise for safer, more effective COVID-19 treatmentsA team of researchers at the University of Alberta has uncovered new antiviral agents that could lead to safer and more effective COVID-19 treatments than other drugs under development. In a recently published paper in the Journal of Medicinal Chemistry, the researchers identified novel protease inhibitor compounds that interfere with the SARS-CoV-2 virus’s ability to replicate…

Mentorship key to breakthrough science in women and children’s health

Placenta in a petri dish is just one innovation that attracts top students and research dollars

Mentorship key to breakthrough science in women and children’s healthJasmine Nguyen signed up for a tour of Meghan Riddell’s cell biology lab as a first-year undergrad in the Faculty of Science and was immediately hooked. “Meghan pulled a placenta out of what was basically a lasagna dish and it was love at first sight,” said Nguyen, who’s now working on her fourth-year honours thesis…